Person

Koeppe, Roger E.

Current interests: 1.Folding and assembly of proteins within membranes. 2.Anchor functions of tryptophan (Trp, or W) at the membrane/water interface. 3.Promotion of ion transport by Trp and fluoro-Trp indoles, and other dipoles. 4.Role of the peptide backbone for ion transport. 5.Chemical substitutions within the peptide backbone. 6.Use of non-genetic amino acids to study protein mechanisms. 7.Chemical mechanisms for voltage-dependent channel gating. 8.Development of molecular force transducers to measure the energetics of membrane thinning. 9.Intrinsic tilt of transmembrane helices.